The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.

The Tennessee Titans placed three safeties on injured reserve after their Week 15 loss to the 49ers, forcing emergency roster moves.

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of the No. 1 seed.

San Francisco 49ers quarterback Brock Purdy has moved into ninth in passing yards in franchise history, surpassing Frankie Albert.

The Denver Broncos and Los Angeles Rams both punched their ticket to the playoffs on Sunday and as of right now, those are the only two teams who have clinched a spot. The Broncos actually have a path to clinch the No. 1 overall seed in the AFC this week, but there's only one scenario where that could happen in Week 16:

Edge rushers and safeties dominated PFF grades. Find out who shined and where the 49ers' defense still faces challenges.

Expert recap and game analysis of the San Francisco 49ers vs. Tennessee Titans NFL game from December 14, 2025 on ESPN.

Learn which TV channel or how to live stream the NFL Week 15 San Francisco 49ers and Tennessee Titans game, Sunday, Dec. 14.

Meanwhile, the 49ers are set to get some much-needed reinforcements on run defense, and Ricky Pearsall's status for Week 16 is unclear.