Various tissues and organs in the human body, such as nerves, heart, bones, and skin, rely on bioelectrical signals to maintain function and support ...
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Remodeling the tumor microenvironment to unlock CAR-T cell potential
Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...
The immune system is the body’s first line of defense when it comes to fighting cancerous cells. It can identify and attack the smallest of threats before they become a danger, and distinguish tumor ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
Researchers have published a comprehensive review exploring the critical role of the "immune microenvironment" in the ...
The field of tumor microenvironment (TME) research has unveiled the crucial influence of acid–base dynamics in shaping cancer progression, metastatic ...
A research team from Fudan University has developed a hydrogel technology based on microenvironment-responsive mechanisms. The material can sense pH changes in the wound environment and dynamically ...
The landscape of breast cancer research is undergoing a significant shift, moving toward complex, combination strategies designed to overcome the body’s own immune suppression.
Cancer cells don’t exist in isolation – instead, they live within a complex ecosystem that also includes immune cells, stromal cells, the extracellular matrix, blood vessels and many other factors.
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