Nucleophilic addition represents a cornerstone of modern organic synthesis, involving the attack of electron-rich species on electrophilic multiple bonds. This class of reactions encompasses additions ...
The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...
A new halide addition reaction represents a means by which halides can be incorporated into biomolecules. The reaction was discovered by chemistry professors Charles L. Perrin and Joseph M. O'Connor ...