The renin–angiotensin system (RAS) is a highly regulated hormonal cascade that plays a central role in the control of blood pressure and the maintenance of renal homeostasis. Its components, including ...

DIASTOLIC hypertension has been described in a variety of clinical settings after bilateral nephrectomy and renal transplantation in man. 1–3 Although its exact etiology has not been clarified, its ...

Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...

Researchers at the University of Virginia School of Medicine have discovered a population of natural barometers that monitor and maintain our blood pressure. The cellular sensors have long been ...

Renin levels are higher in hospitalized patients with acute kidney injury than patients without the condition, a new study finds. High renin levels may be a biomarker for worse outcomes in ...

A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study. A mutation in a gene that helps regulate high blood pressure is a cause ...

Utility of the Breast Cancer Index (BCI) in the clinical practice. CD205, a target antigen for a novel ADC: Evaluation of antigen expression on TNBC, pancreatic adenocarcinoma and bladder urothelial ...

Testing for aldosterone levels may hold the key to treatment-resistant hypertension and many other cardiac conditions, but what is the optimal approach to regulating this hormone?

Hypertension is a serious condition affecting millions. Currently there are seven classes of drugs used to reduce blood pressure. Aliskiren (Tekturna®, Rasilez®) is the first of a new class of orally ...

Weill Medical College of Cornell University researchers have made the startling discovery that renin -- a kidney-secreted enzyme crucial to blood pressure regulation -- is also synthesized and ...

Lower estimated tubular secretion was found to be associated with a faster decline of estimated glomerular filtration rate (eGFR) but wasn’t associated with progression of chronic kidney disease or ...