Pancreatic cancer is one of the most aggressive and difficult-to-treat cancers. One reason for its resistance to therapy is ...

A seven-cohort single-cell atlas links early-onset colorectal cancer to coordinated epithelial, stromal and NOTCH-associated ...

Researchers reprogrammed an 80-year-old's blood cells to an epigenetic age below 20, creating a lab model for studying ...

A single dose of ORK1 generated durable disease control in two independent inflammatory bowel disease mouse models ORK1 induced sustained myeloid ...

Cellular reprogramming enables scientists to reset the biological clock of mature human cells without stripping away their ...

Metabolic reprogramming is a defining hallmark of CRC. The Warburg effect is the principal metabolic feature of CRC cells, wherein glucose is preferentially catabolized into lactate to sustain ...

Cyclic induction of the Yamanaka reprogramming factors for four weeks before stroke reduced ischemic brain damage, preserved ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the "recipe" for the transformation. Researchers at Lund University have now created ...