Quarterback Drew Pyne is leaving Missouri after one season and again entering the transfer portal as he looks to move to his fourth school, sources told ESPN.

Missouri football quarterback Drew Pyne is entering the transfer portal. Here’s how that changes the picture for Mizzou’s room in 2025.

Pyne joined Mizzou as the backup to longtime Tigers QB Brady Cook and appeared in six games with two starts (due to a Cook injury). Most notably, Pyne led the Tigers in their wild fourth-quarter comeback win over Oklahoma, with Zion Young’s scoop-and-score fumble return with 22 seconds left giving Mizzou the win.