The Tennessee Titans placed three safeties on injured reserve after their Week 15 loss to the 49ers, forcing emergency roster ...

When Daniel Jones went down for the season with a torn Achilles, the 49ers probably figured their upcoming game against the ...

The 49ers have to start accepting the cold, hard truth about Ricky Pearsall.

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the ...

San Francisco 49ers quarterback Brock Purdy has moved into ninth in passing yards in franchise history, surpassing Frankie ...

Edge rushers and safeties dominated PFF grades. Find out who shined and where the 49ers' defense still faces challenges.

By the end of Week 16, 11 of the NFL's 14 playoff spots could be clinched ...

After cruising through an easier schedule, the 49ers will face the Colts, Bears and Seahawks to end season.

San Francisco 49ers quarterback Brock Purdy (13) runs the ball past Tennessee Titans linebacker Cedric Gray, left, during the ...

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of ...

Indianapolis Colts' head coach Shane Steichen confirmed on Monday that Phillip Rivers will start in next week's game against ...

Tennessee lost 37-24 to the San Francisco 49ers on Dec. 14 at Levi's Stadium, with the 49ers scoring on their first five ...