Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research ...

Am J Health Syst Pharm. 2009;66(8):715-726. Mechanism of action of maraviroc. Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of ...

Tests in animal models by researchers at the Lewis Katz School of Medicine at Temple University, and at the University of Nebraska Medical Center (UNMC) have shown how gene editing two targets, HIV-1 ...

Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of ...

HIV is a lifelong infection that, without proper antiviral treatment, will kill cells of the immune system and leave individuals susceptible to infections and cancers. The longevity of this virus ...

Duke Human Vaccine Institute (DHVI) investigators used a technique called time-resolved, temperature-jump (TR, T-Jump) small-angle x-ray scattering (SAXS) to capture the spectacularly brief moment ...

Am J Health Syst Pharm. 2009;66(8):715-726. Since MOTIVATE 1 and MOTIVATE 2 used identical study designs and endpoints, the results of the two trials were pooled for further analysis. [29] The ...