How are disease-relevant molecules distributed within tissue? What changes occur even before they become visible under the ...

Researchers at the Leibniz-Institut für Analytische Wissenschaften – ISAS have, for the first time, succeeded in combining two complementary analytical methods to create a high-resolution molecular ...

The formation of supramolecular polymers within living cells is an emerging strategy for regulating cellular functions, and ...

With wider use of antihypertensive and lipid-lowering therapies, people with overweight/obesity may reach similar blood ...

In addition to providing energy, lipids are also essential building blocks of our cell membranes. However, despite their importance, they remain poorly understood. For the first time, a team from the ...

Lipids are essential regulators of cellular identity, organelle biogenesis, signaling, and metabolic adaptation. Yet fundamental principles remain unresolved: How do cells decide when to store, ...

Peripheral artery disease (PAD), defined by stenosis or occlusion of the extremities (particularly the lower extremities), affects 200 million individuals worldwide, including an estimated 7% of ...

This fundamental study presents a compelling and comprehensive analysis of the newly defined Lipocone superfamily, offering unprecedented insights into the evolutionary origins of Wnt proteins. The ...

The conventional view of lipids as a structural components or energy reservoirs have recently gained a more dynamic paradigm. Lipids are now a central molecular regulator in endocrine biology—act as ...

Researchers at EPFL have created the first 4D lipid atlas of vertebrate development, revealing how fats shape our bodies from embryo to organism. We often think of embryonic development as a genetic ...