According to the RNA world hypothesis, life began when RNA molecules evolved the ability to make more copies of themselves. Now we have discovered an RNA molecule that is almost capable of this – it ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

A new study reveals how cells activate an emergency DNA repair system when their usual defenses fail, especially under the stress of tangled RNA–DNA structures called R-loops. Credit: Stock Scripps ...

Viruses in water pose major public health threats, yet their structural diversity makes them unequally susceptibility to disinfection. This study systematically explored how reactive oxygen species ...

Human cytomegalovirus (HCMV) is a large double-stranded DNA virus with a protracted replication cycle spanning several days, during which time it extensively remodels cellular architecture. Here, we ...

James Dewey Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped launch a revolution in biology and medicine, died Thursday at age 97. He died in hospice care after a brief ...

James D. Watson, whose co-discovery of the twisted-ladder structure of DNA in 1953 helped light the long fuse on a revolution in medicine, crimefighting, genealogy and ethics, has died. He was 97. The ...

Often celebrated as a pioneer of genetics alongside Francis Crick, racist and sexist remarks tarnished his reputation in later years. James Watson was credited as the co-discoverer of the structure of ...

We thank all the members of the Symington lab for review of the manuscript. This work was supported by grants from the NIH (R35 GM126997 to L.S.S. and T32 CA265828 to M.J.J.). Schematics shown in the ...

Dublin is known as a city where you can enjoy a few pints of Guiness, get a warm welcome from the locals and hear lively traditional music drifting out of pubs and into the city air. But it’s not just ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...