Vascular Ehlers-Danlos syndrome (vEDS) is a heritable connective tissue disorder that makes the connective tissue very fragile, particularly in the blood vessels and hollow organs. vEDS can cause life-threatening complications, such as aneurysm, dissection, and rupture of the arteries and rupture of organs, mainly the bowel. Genetic testing is used to see if a person has a genetic variant that causes vEDS. Genetic testing should be considered if a person has any of the major criteria or several